Individually wrapped. Precision Cleaning for Hard-to-Reach Spaces. Don't settle for an incomplete clean. PRO-SYS® interdental brushes gently remove plaque from places where toothbrushes and floss don't. For cleaning between braces, crowns, bridges and implants. Also great for back teeth and crowned teeth. Dentist recommended. Manufactured from DuPont bristles and German stainless steel.