The dentist-loved toothpaste that's beautiful on the inside and out. Twice’s modern toothpaste formula combines health, wellness, whitening and more - made by world-class experts. Dentist-recommended doses of fluoride and potassium nitrate + mouth-healthy vitamins A, C, E + soothing aloe vera with none of the not-so-good-for-you and unnecessary additives. EARLY BIRD Morning: Awakening + Invigorating Consider Early Bird your mouth’s minty wake-up call, for whenever it needs to hit refresh. Squeeze a little wintergreen and peppermint into your morning routine to feel clean, confident and ready to take on the day—with a smile, of course. TWILIGHT Evening: Calming + Soothing Like a spa moment for your smile, Twilight puts the “oo” in smooth. Both relaxing and refreshing, lavender, vanilla and peppermint form a dream team of flavors that will become your favorite way to say goodnight. From our dental expert, Dr. Jonathan B. Levine: “I helped formulate Twice and I proudly give it to every one of my patients. The combination of fluoride and potassium nitrate does a great job of preventing cavities, protecting against sensitivity and strengthening enamel. These ingredients combined do a great job! The silicates and pentasodium triphosphate in Twice help safely and effectively polish the tooth enamel and remove plaque and stains to help whiten without being too harsh and abrasive (like charcoal can be). The trio of vitamins and antioxidants work well together to balance bacteria in the mouth and promote a healthy ecosystem. Why do you need that? Because oxidative stresses from free radicals need to be neutralized in the mouth. I also like the standard of care taken in creating Twice. It is SLS free. Not many are. SLS can cause ulcers and sores in the mouth. Check your labels! I recommend Twice toothpaste, and I use it every morning and every night. You’re going to love it!” (About Dr. Levine: Member of Dr. Oz’s Medical Advisory Board, Former oral health expert to Oral-B and Sensodyne, Award winning dental specialist, Associate Professor, NYU Dental School, Board Member, BU Goldman School of Dentistry, Founder of Glo Science, Founder of GoSmile, 28 dental patents granted, Author of Smile!: The Ultimate Guide to Achieving Smile Beauty) Key Benefits / Ingredients Teeth Whitening: Hydrated Silica + Pentasodium Triphosphate A delicate blend of silicates polishes the surface stains of the teeth and pentasodium triphosphate goes deep to help remove plaque. The result is a clean, glistening smile. Cavity Prevention + Enamel Health: Sodium Fluoride The most powerful and science-backed ingredient known to prevent painful cavities and strengthen the enamel for strong, healthy teeth. Sensitivity Relief: Potassium Nitrate Potassium nitrate builds protection against painful sensitivity by blocking the nerves of your teeth from exposure to discomfort. It usually takes a week of usage before results are seen and felt. Triple Antioxidant Complex: Vitamin A (as Retinyl Palmitate), Vitamin C (as Sodium Ascorbyl Phosphate), Vitamin E (as Tocopherol) These three powerful antioxidants work together to help fight free radicals, strengthen gums, promote collagen production, and maintain good bacteria levels for a healthier mouth. Botanical Extracts: Aloe Vera, Lavender, Wintergreen, Peppermint A powerful healing blend of botanicals that help soothe inflammation, reduce pain, freshen breath, and hydrate gums. Full List of Ingredients: Potassium Nitrate, Sodium Fluoride, Hydrated Silica, Sorbitol, Glycerin, Pentasodium Triphosphate, Cocamidopropyl Betaine, Sodium Ascorbyl Phosphate (Vitamin C), Retinyl Palmitate (Vitamin A), Tocopherol (Vitamin E), Aloe Barbadensis Leaf Juice (Aloe Vera), Flavor, Lauryl Glucoside, Sodium Saccharin, Xylitol, Sucralose, Cellulose Gum, Titanium Dioxide, Sodium Benzoate, Citric Acid, Water.