InterOss® is a natural hydroxyapatite bone grafting material derived from Australia bovine bone (BSE free). This highly purified osteoconductive material is produced from natural bone through a multi-step purification process. Its natural origin makes InterOss® chemically and structurally comparable to mineralized human bone (nanocrystalline natural apatite). InterOss® is available in granule form. It is supplied sterile and is dedicated for single use. The presence of a macroporous structure favors cell ingrowth, while the micropores allow the penetration of body fluids into the implant. The microporosity can also be used to manipulate resorption and dissolution rate: the greater the microporosity, the greater the degradation rate.